TP53

About

Location: 17p13.1

Mappings

HGNC: HGNC:11998

Ensembl: ENSG00000141510

NCBI: 7157

Refseq: NM_000546.6

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Biomarkers

TP53 is involved in the following curated biomarkers.

Name Biomarker type Propositions Statements
TP53 Somatic variants Somatic variant 2 2
TP53 deletion Copy number 2 2
Wild type TP53 Wild type 1 1

Therapeutic response

Precision oncology relationships for therapeutic response involving this gene.

Organizations Biomarkers Cancer types Therapies
EMA (1) TP53 Somatic variants Chronic Lymphocytic Leukemia Venetoclax
EMA (1) TP53 deletion Chronic Lymphocytic Leukemia Venetoclax
EMA (1) Wild type TP53 Chronic Lymphocytic Leukemia Venetoclax
EMA (1) TP53 deletion Chronic Lymphocytic Leukemia Idelalisib, Rituximab
EMA (1) TP53 Somatic variants Chronic Lymphocytic Leukemia Idelalisib, Rituximab