Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:12

    Therapeutic Response

    ER positive and HER2-negative status confers therapeutic sensitivity to Abemaciclib in patients with Invasive Breast Carcinoma.

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    Statements

    Source and description
    Verzenio (abemaciclib) [package insert]. FDA.

    The U.S. Food and Drug Administration (FDA) granted approval to abemaciclib for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer with disease progression following endocrine therapy and prior chemotherapy in the metastatic setting.

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