Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:230

    Therapeutic Response

    PD-L1 >= 1% status confers therapeutic sensitivity to Ipilimumab in combination with Nivolumab in patients with Non-Small Cell Lung Cancer.

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    Statements

    Source and description
    Opdivo (nivolumab) [package insert]. FDA.

    The U.S. Food and Drug Administration (FDA) granted approval to nivolumab in combination with ipilimumab for the first-line treatment of adult patients with metastatic non-small cell lung cancer expressing PD-L1 (>= 1%) as determined by an FDA-approved test, with no EGFR or ALK genomic tumor aberrations.

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