Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:386

    Therapeutic Response

    CD20 + status confers therapeutic sensitivity to Cyclophosphamide in combination with Fludarabine and Rituximab in patients with Chronic Lymphocytic Leukemia.

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    Statements

    Source and description
    Rituxan (rituximab) [package insert]. FDA.

    The U.S. Food and Drug Administration granted approval to rituximab in combination with fludarabine and cyclophosphamide for the treatment of previously untreated and previously treated CD20-positive Chronic Lymphocytic Leukemia (CLL).

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