Therapeutic Response

ER negative, HER2-negative, and PR negative status confers therapeutic sensitivity to Sacituzumab govitecan in patients with Invasive Breast Carcinoma.

Statements

Source and description
Trodelvy (sacituzumab govitecan) [package insert]. FDA. The U.S. Food and Drug Administration granted approval to sacituzumab govitecan for the treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (mTNBC) who have received two or more prior systemic therapies, at least one of them for metastatic disease.
Trodelvy (sacituzumab govitecan) [product information]. EMA. The European Medicines Agency (EMA) has authorized sacituzumab govitecan for the treatment of adult patients with unresectable or metastatic triple-negative breast cancer (mTNBC) who have received two or more prior systemic therapies, including at least one of them for advanced disease.
Trodelvy (sacituzumab govitecan) [product information]. EMA. The European Medicines Agency (EMA) has authorized sacituzumab govitecan as a monotherapy for the treatment of adult patients with locally advanced or metastatic triple-negative breast cancer (TNBC) who have not received prior systemic therapy for metastatic disease and who are not candidates for PD-1 or PD-L1 inhibitor therapy.