Molecular Oncology Almanac
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    2. prop:vtxr:409

    Therapeutic Response

    v::RET status confers therapeutic sensitivity to Selpercatinib in patients with Anaplastic Thyroid Cancer.

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    Retevmo (selpercatinib) [package insert]. FDA.

    The U.S. Food and Drug Administration granted accelerated approval to selpercatinib for the treatment of treatment of adult and pediatric patients 2 years of age and older with advanced or metastatic thyroid cancer with a RET gene fusion, as detected by an FDA-approved test, who require systemic therapy and who are radioactive iodine-refractory (if radioactive iodine is appropriate).

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