Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:459

    Therapeutic Response

    TSC2 oncogenic variants status confers therapeutic sensitivity to Everolimus in patients with Renal Angiomyolipoma.

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    Statements

    Source and description
    Afinitor (everolimus) [package insert]. FDA.

    The U.S. Food and Drug Administration granted approval to everolimus for the treatment of adult patients with renal angiomyolipoma and tuberous sclerosis complex (TSC), not requiring immediate surgery.

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