Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:547

    Therapeutic Response

    v::RET status confers therapeutic sensitivity to Vandetanib in patients with Medullary Thyroid Cancer.

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    Statements

    Source and description
    Caprelsa (vandetanib) [product information]. EMA.

    The European Medicines Agency (EMA) has authorized vandetanib for the treatment of aggressive and symptomatic Rearranged during Transfection (RET) mutant medullary thyroid cancer (MTC) in patients with unresectable locally advanced or metastatic disease. Vandetanib is indicated in adults, children, and adolescents aged 5 years and older.

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