Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:553

    Therapeutic Response

    ERBB2 amplification status confers therapeutic sensitivity to Trastuzumab deruxtecan in patients with Adenocarcinoma of the Gastroesophageal Junction.

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    Statements

    Source and description
    Enhertu (trastuzumab deruxtecan) [product information]. EMA.

    The European Medicines Agency (EMA) has authorized trastuzumab deruxtecan as a monotherapy for the treatment of adult patients with advanced HER2-positive gastric or gastroesophageal junction (GEJ) adenocarcinoma who have received a prior trastuzumab-based regime.

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