Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:587

    Therapeutic Response

    MSI-H status confers therapeutic sensitivity to Dostarlimab in patients with Endometrial Carcinoma.

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    Statements

    Source and description
    Jemperli (dostarlimab) [product information]. EMA.

    The European Medicines Agency (EMA) has authorized dostarlimab as a monotherapy for the treatment of adult patients with mismatch repair deficiency (dMMR) / microsatellite instability-high (MSI-H) recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing regimen.

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