Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:588

    Therapeutic Response

    PD-L1 >= 50%, Wild type ALK, and Wild type EGFR status confers therapeutic sensitivity to Pembrolizumab in patients with Non-Small Cell Lung Cancer.

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    Statements

    Source and description
    Keytruda (pembrolizumab) [product information]. EMA.

    The European Medicines Agency (EMA) has authorized pembrolizumab as a monotherapy for the first-line treatment of metastatic non-small cell lung carcinoma in adult patients whose tumors express PD-L1 with a >= 50% tumor proportion score (TPS) with no EGFR or ALK positive tumor mutations.

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