Molecular Oncology Almanac
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    1. Propositions
    2. prop:vtxr:679

    Therapeutic Response

    ER negative, HER2-negative, PD-L1 >= 1%, and PR negative status confers therapeutic sensitivity to Atezolizumab in combination with Nab-paclitaxel in patients with Invasive Breast Carcinoma.

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    Statements

    Source and description
    Tecentriq (atezolizumab) [product information]. EMA.

    The European Medicines Agency (EMA) has authorized atezolizumab in combination with nab-paclitaxel for the treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer whose tumors have PD-L1 expression >= 1% and who have not received prior chemotherapy for metastatic disease.

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