PTEN deletion

Biomarker type: Copy number

Gene context: PTEN

Copy change: loss

Precision oncology relationships for therapeutic response involving this biomarker.

Organizations

Biomarkers

Cancer types

Therapies

Organizations	Biomarkers	Cancer types	Therapies
EMA (1) FDA (2)	ER positive, HER2-negative, PTEN deletion	Invasive Breast Carcinoma	Capivasertib, Fulvestrant
FDA (2)	HER2-negative, PR positive, PTEN deletion	Invasive Breast Carcinoma	Capivasertib, Fulvestrant
FDA (2)	ER positive, HER2-negative, PR positive, PTEN deletion	Invasive Breast Carcinoma	Capivasertib, Fulvestrant