AKT1 amplification

Biomarker type: Copy number

Gene context: AKT1

Copy change: gain

Precision oncology relationships for therapeutic response involving this biomarker.

Organizations

Biomarkers

Cancer types

Therapies

Organizations	Biomarkers	Cancer types	Therapies
EMA (1) FDA (2)	AKT1 amplification, ER positive, HER2-negative	Invasive Breast Carcinoma	Capivasertib, Fulvestrant
FDA (2)	AKT1 amplification, HER2-negative, PR positive	Invasive Breast Carcinoma	Capivasertib, Fulvestrant
FDA (2)	AKT1 amplification, ER positive, HER2-negative, PR positive	Invasive Breast Carcinoma	Capivasertib, Fulvestrant